Granular myringitis (GM) is a long term condition in which there is inflammation of the tympanic membrane in the ear and formation of granulation tissue within. Granular Myringitis (GM) is a chronic inflammation that is confined to the squamous layer of the Tympanic. Membrane (TM). It was considered. The Granular Myringitis (GM) is not uncommon though in medical literature it has been reported among the rarer conditions. The aim of this article is to review.
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Fifty-eight publications granulag identified, dating from to ; 46 of these were potentially relevant. Acceptable interventions included any topical or oral therapy or surgical management. In some of the refractory cases granulations are removed and the raw area is covered with skin.
This review addressed a clear clinical question with detailed inclusion criteria that appear to have been adhered to. Eligible studies had to include myringtis least 20 patients with a clinical diagnosis of granular myringitis based on clinical history and examination and lasting at least three weeks.
The primary outcome measure was disease recurrence. The authors did not state how papers were selected for review or how many reviewers performed the selection.
This is a critical abstract of a systematic review that meets the criteria for inclusion on DARE. The primary outcome measured was the effect of the proposed intervention on recurrence of granular myringitis, compared with empirical antibiotic therapy.
These data were then used to calculate a risk difference RD and number needed to treat NNT for each study.
Granular myringitis – Wikipedia
Cochrane Database Syst Rev. Combined tympanic epithelial layer avulsion and overlay myringoplasty for diffuse granular myringitis. A narrative synthesis was appropriate given the heterogeneity, but the small sample size and myrungitis quality of the included studies make the conclusions appear much stronger than warranted by the limited evidence. The clinical features and pathogenesis of myringitis granulosa.
Granular myringitis: a review.
CRD summary The review concludes that dilute vinegar solution should be considered over conventional antibiotic drops for the treatment of granular myringitis. Studies of patients with co-morbid middle-ear disease were excluded from the review as were patients with diagnoses based solely on clinical history.
Vinegar treatment in the management of granular myringitis. It is not clear if non-English language studies were included. If perforation occurs the underlay perichondrium or temporalis fascia grafting is done. Data extraction For each included study, the reviewers appear to have extracted data on recurrence for each treatment group.
For each included study, the reviewers appear to have extracted data on recurrence for each treatment group. The methodology of this review was poorly reported — for example, there were no details on the study selection, quality assessment or data extraction phases — so it was difficult to judge the extent to which various sources of error and bias may have influenced the process and final results.
Centre for Reviews and Dissemination UK ; There was a reduced recurrence of granular myringitis in both studies’ intervention groups, although neither study was randomised or blinded, making it difficult to assess the clinical relevance of the results.
The authors stated that randomised controlled trials are required to assess strategies to treat and reduce the recurrence of granular myringitis, including surgical debridement, endoscopy-aided laser therapy, cautery and topical application of low pH solutions.
The review concludes that dilute vinegar solution should be considered over conventional antibiotic drops for the treatment of granular myringitis. Authors’ objectives To establish optimal management and intervention strategies for granular myringitis.
The granulations are either localized or diffuse. Email this article Login required. The ensuing fibrosis in patients with granulations of deep bony meatal wall can result into an atresia of the deep bony EAC. Further research of high value is needed. Trauma and infections of the external ear.
Two studies were included in the review: Clear Turn Off Turn On. Management of granular myringitis: Clinical characteristics of granular myringitis treated with myrinitis solution.
However many patients have a sensation of fullness, irritation, mild pain or itching in the ear. Otolaryngol Head Neck Surg.
Granular myringitis: a review.
Data were retrieved from the selected studies and checked for accuracy and consistency. The granulations over tympanic membrane continue to grow slowly for years. Each critical abstract contains a brief summary of the review methods, results and conclusions followed by a detailed critical assessment on the reliability of the review and the conclusions drawn. Authors’ conclusions Alternative therapies such as dilute vinegar solution should be considered over conventional antibiotic drops tranular treating granular myringitis.
User Username Password Remember granjlar. Results of the review Two studies were included in the review: If patients do not respond then application of topical caustic agents are employed.
Otorinolaringologia 2004 September;54(3):175-8
Article Tools Print this article. Topical 5-fluorouracil for granular myringitis: Untreated, granular myringitis can lead to post-inflammatory medial external auditory canal fibrosis, acquired canal atresia and inflammatory infiltration of the deep canal.
Alternative therapies such as dilute vinegar solution should be considered over conventional antibiotic drops when treating granular myringitis. The authors did not state how the data were extracted for this review or how many reviewers performed the data extraction. Keywords Granular myringitis, Tympanic membrane, External auditory canal, Granular otitis externa, Otitis. Management of granular myringitis: Publication bias cannot be ruled out.